Primary Identifier | MGI:5302230 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Rax |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A targeting vector was used to insert flox sites upstream of exon 1 and intron 2 by homologous recombination in ES cells. An Frt-flanked PGK-neo selection cassette was inserted also, and removed after selection of correctly targeted clones by Flp recombinase. Cre-mediated recombination will result in excision of exons 1 and 2 of Rax, producing a null allele. |