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Allele : Krt6a/Krt6b<tm1Der> keratin 6B; targeted mutation 1, Dennis R Roop
Primary Identifier  MGI:2388396 Allele Type  Targeted
Attribute String  Null/knockout Gene  Krt6b
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  An 18 kb region containing the entire coding sequences of Krt2-6a and Krt-6b, and including 10.5 kb of intervening sequences, was deleted and replaced with an HPRT-neo minigene via homologous recombination. Absence of expression of both genes in homozygous mutant animals was confirmed by RNase protection assay of skin and hair follicles. 1
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • K6ab-null,
  • K6ab-null,
  • MK6a/b<->,
  • MK6a/b<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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5 Publication categories

Trail: Allele




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