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Allele : Lias<tm2.1Mae> lipoic acid synthetase; targeted mutation 2.1, Nobuyo Maeda

Primary Identifier  MGI:5810126 Allele Type  Targeted
Attribute String  Hypomorph Gene  Lias
Transmission  Germline Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
description  ES cell line - Chemicon B/6N
molecularNote  The targeting vector consists of a loxP site, the 3' UTR sequence of the bovine growth hormone gene, a neomycin cassette and a loxP site followed by the 3'-UTR sequence of the cFos gene. Cre-mediated recombination removed the bovine growth hormone gene and neo cassette, allowing cFos to drive expression of the endogenous gene. Expression is 25% of the endogenous gene expression.
  • mutations:
  • Insertion
  • synonyms:
  • Lias<Low>,
  • Lias<Low>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele