| First Author | Marker PC | Year | 1995 |
| Journal | Genomics | Volume | 28 |
| Issue | 3 | Pages | 576-80 |
| PubMed ID | 7490098 | Mgi Jnum | J:28411 |
| Mgi Id | MGI:76029 | Doi | 10.1006/geno.1995.1192 |
| Citation | Marker PC, et al. (1995) Chromosomal localization, embryonic expression, and imprinting tests for Bmp7 on distal mouse chromosome 2. Genomics 28(3):576-80 |
| abstractText | Murine Bmp7 has been assigned to distal Chromosome 2 by interspecific backcross mapping. The map location suggests close linkage to classical mouse mutations and places Bmp7 within a chromosome region thought to contain one or more unidentified imprinted genes. A direct test suggests that Bmp7 is not imprinted. An examination of embryonic RNA expression patterns shows that Bmp7 is expressed in a variety of skeletal and nonskeletal tissues. Both embryonic expression patterns and the human chromosomal sublocalization inferred from its mouse location make Bmp7 a candidate for the gene affected in some patients with Holt-Oram syndrome. |
