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Allele : Ndrg1<em1Lxli> N-myc downstream regulated gene 1; endonuclease-mediated mutation 1, Li-Xi Li

Primary Identifier  MGI:7366891 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ndrg1
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology using sgRNAs GGGCCAACAACTTCCCATTCTGG and GTGTGACACCCCTTGTCTTGGGG generated an approximate 3.5 kb deletion encompassing exons 4 and 5. Western blot analysis confirmed the absence of protein in the sciatic nerve.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele