Primary Identifier | MGI:2449180 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Ercc8 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by insertion of a PGK-hygro cassette into exon 2 (at amino acid 42) via homologous recombination. Absence of gene expression was verified by Western blot analysis of homozygous mutant MEFs using an antibody directed against the C-terminal domain of the human protein. |