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Protein Coding Gene : Ciao3 cytosolic iron-sulfur assembly component 3
Primary Identifier  MGI:1914813 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  67563
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Acts upstream of or within hematopoietic progenitor cell differentiation and iron-sulfur cluster assembly. Predicted to be part of cytosolic [4Fe-4S] assembly targeting complex. Orthologous to human CIAO3 (cytosolic iron-sulfur assembly component 3).
PHENOTYPE: Mice homozygous for a targeted knock-out die before E10.5. Mice heterozygous for a targeted allele exhibit partial lethality between E10.5 and birth. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI504405,
  • cytosolic iron-sulfur assembly component 3,
  • Ciao3,
  • nuclear prelamin A recognition factor-like,
  • MGI:2146884,
  • MGI:6286362,
  • 9030612I22Rik,
  • AI504405,
  • RIKEN cDNA 9030612I22 gene,
  • Narfl
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2 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> Exons in specific strains

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