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Allele : Lmf1<cld> lipase maturation factor 1; combined lipase deficiency

Primary Identifier  MGI:1856820 Allele Type  Spontaneous
Gene  Lmf1 Inheritance Mode  Recessive
Strain of Origin  M. m. musculus (Northern Jutland, Denmark) Is Recombinase  false
Is Wild Type  false
description  Lmf1 tw73lab is one of three spontaneous, recessive, lethal mutations found in a wild-derived t haplotype. The other mutations are tw73 and tw73lab.
molecularNote  This mutation was found as a "parasitic lethal" in tw73 and recovered from the haplotype by recombination. A full-length murine endogenous retrovirus (MuERV) is inserted into intron 7. This results in the expression of an aberrant mRNA that contains sequences derived from exons 1-7, but is missing sequences derived from exons 8-11. 400 bp of viral sequence replaced the missing sequences in the mRNA.
  • mutations:
  • Viral insertion
  • synonyms:
  • cld,
  • cld
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

12 Publication categories

Trail: Allele