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Allele : Tg(Thy1-PFN1*C71G)67Zxu transgene insertion 67, Zuoshang Xu
Primary Identifier  MGI:5796269 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Thy1-PFN1*C71G)67Zxu
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  The transgenic construct contains a mutant human profilin 1 cDNA sequence with a V5 tag (45 bp) fused to the N-terminus and inserted downstream of the modified ~6.5 kbp mouse Thy1.2 promoter sequences. PFN1 harbors the C71G mutation associated with amyotrophic lateral sclerosis (ALS).
  • mutations:
  • Insertion
  • synonyms:
  • Thy1.2-PFN1<C71G>,
  • Thy1.2-PFN1<C71G>
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1 Expresses

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0 Mutation Involves

Phenotype

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