| First Author | Kumagai A | Year | 2003 |
| Journal | Bioorg Med Chem | Volume | 11 |
| Issue | 23 | Pages | 5143-8 |
| PubMed ID | 14604677 | Mgi Jnum | J:86482 |
| Mgi Id | MGI:2680229 | Doi | 10.1016/j.bmc.2003.08.016 |
| Citation | Kumagai A, et al. (2003) Tumor chemopreventive activity of 3-O-acylated (-)-epigallocatechins. Bioorg Med Chem 11(23):5143-8 |
| abstractText | In order to seek promising cancer chemopreventive agents, we assessed the antitumor promoting activities of 3-O-octanoyl- or 3-O-(2-methyloctanoyl)-(-)-epigallocatechins, inhibiting markedly the activation of Epstein-Barr virus early antigen, in a two-stage mouse skin carcinogenesis assay. As a result, these derivatives inhibited a papilloma formation 1.3-1.6-fold more strongly than (-)-epigallocatechin gallate well established as anti-tumor promoter. |
