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Publication : The Id proteins and angiogenesis.

First Author  Benezra R Year  2001
Journal  Oncogene Volume  20
Issue  58 Pages  8334-41
PubMed ID  11840326 Mgi Jnum  J:74550
Mgi Id  MGI:2158609 Doi  10.1038/sj.onc.1205160
Citation  Benezra R, et al. (2001) The Id proteins and angiogenesis. Oncogene 20(58):8334-41
abstractText  Since the identification of the Id proteins over a decade ago, a great many cell cycle and cell fate decisions have been shown to be under the control of these proteins as described in other sections of this review issue. Perhaps the most unsuspected activity of this class of proteins has been their essential role in angiogenesis, both in the forebrain during development and during the growth and metastasis of tumors in adults. This section of the review issue will focus on the key observations which have led to these conclusions, speculations about potential mechanisms and the outlook for potential therapeutic interventions.
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