Primary Identifier | MGI:104838 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 219140 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable guanyl-nucleotide exchange factor activity and identical protein binding activity. Predicted to be involved in cell migration; plasma membrane bounded cell projection assembly; and regulation of cell migration. Predicted to be located in several cellular components, including filopodium; lamellipodium; and ruffle membrane. Predicted to be active in cytosol. Is expressed in brain; liver; testis; thymus primordium; and vertebral cartilage condensation. Orthologous to human SPATA13 (spermatogenesis associated 13). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and overtly normal. Behavioral tests indicate that mutant mice exhibit submissive social hierarchy behavior and females exhibit increased voluntary activity in the dark phase of the light-dark cycle. [provided by MGI curators] |