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Transgene : Tg(CD46)2Gsv transgene insertion 2, Frank Grosveld
Primary Identifier  MGI:3688751 Organism  mouse, laboratory
Chromosome  9 Mgi Type  transgene
description  PHENOTYPE: Transgenic mice show protection from hyperacute rejection (HAR) after tissue transplantation likely due to human complement inactivation. Expresseion of CD46 makes mice susceptible to measles virus (MV) infection, providing a small animal model of MV infection. [provided by MGI curators]
  • synonyms:
  • MCP YAC,
  • Tg(CD46)2Gsv,
  • transgene insertion 2, Frank Grosveld,
  • Tg(MCP)Olds2,
  • YAC CD46 line 2,
  • MCP-YAC line 2,
  • YAC-CD46,
  • MY II,
  • Tg(CD46)2Olds
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