Primary Identifier | MGI:3038661 | Allele Type | QTL |
Gene | Hdlq16 | Inheritance Mode | Not Specified |
Strain of Origin | 129S1/SvImJ | Is Recombinase | false |
Is Wild Type | false |
description | Hdlq16 also interacts with Hdlq1 on chromosome 5. Homozygosity for 129S1/SvImJ-derived allele at both Hdlq1 and Hdlq16 significantly decreased plasma HDL concentration in male and female animals fed a CHOW diet. |
molecularNote | This allele confers increased HDL cholesterol levels on an atherogenic diet compared to C57BL/6J. |