Primary Identifier | MGI:1856905 | Allele Type | Spontaneous |
Gene | Trf | Inheritance Mode | Recessive |
Strain of Origin | BALB/cJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A G-to-A point mutation in the first nucleotide of intron 16 eliminates exon 16 splice donor site C-GT by changing it to C-AT. This results in mis-splicing, including the use of a cryptic splice donor 27 bp upstream, deleting 9 codons. A small amount of mutant protein is detectable. |