Primary Identifier | MGI:107818 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 17534 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Predicted to enable carbohydrate binding activity; collagen binding activity; and signaling receptor activity. Predicted to be involved in collagen catabolic process. Predicted to act upstream of or within endocytosis. Predicted to be located in cell surface. Is expressed in several structures, including brain; head bone; meninges; metanephros; and respiratory system. Orthologous to human MRC2 (mannose receptor C type 2). PHENOTYPE: Homozygous mice are visibly normal, viable and have no reproductive defects. Mouse embryonic fibroblasts derived from null mice exhibit decreased migration while bone marrow-derived macrophages exhibit increased migration. [provided by MGI curators] |