| Primary Identifier | MGI:5496055 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Malat1 |
| Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of the coding sequence. An additional loxP site was inserted 1.5 kb downstream of the translation initiation site. Flp-mediated recombination removed the neomycin resistance cassette and left a portion of the coding sequence floxed. Cre-mediated recombination removed the floxed portion of the coding sequence. Northern blot analysis confirmed the absence of transcript expression in the brain and liver. |
