Primary Identifier | MGI:1338917 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 20193 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including ATPase binding activity; S100 protein binding activity; and protein homodimerization activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of sprouting angiogenesis. Located in sarcoplasmic reticulum. Is expressed in several structures, including brain; heart; inner ear; musculature; and urothelium. Orthologous to human S100A1 (S100 calcium binding protein A1). PHENOTYPE: Homozygous and heterozygous mice exhibit a reduced cardiac contractility in response to chronic hemodynamic stress. [provided by MGI curators] |