Primary Identifier | MGI:6157626 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Tardbp |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 methodologies were used to introduce a 1 bp base pair mutation (C>A) resulting in a Q331K point mutation. The Q331K mutation is associated with Amyotrophic Lateral Sclerosis. |