|  Help  |  About  |  Contact Us

Publication : Evaluating the IgMi mouse as a novel tool to study B-cell biology.

First Author  Sahputra R Year  2018
Journal  Eur J Immunol Volume  48
Issue  12 Pages  2068-2071
PubMed ID  30315705 Mgi Jnum  J:269485
Mgi Id  MGI:6259985 Doi  10.1002/eji.201847735
Citation  Sahputra R, et al. (2018) Evaluating the IgMi mouse as a novel tool to study B-cell biology. Eur J Immunol 48(12):2068-2071
abstractText  The IgMi mouse fails to secrete antibodies or class switch its BCR from IgM. Our study reveals that other cellular compartments, including B-cell subsets, DC subsets, GC B cells and TFH cells are perturbed in the IgMi mouse, thus presenting important additional considerations when using the mouse to explore the role of secreted antibody.
Quick Links:
 
Quick Links:
 

Expression

Publication --> Expression annotations

 

Other

3 Bio Entities

0 Expression