First Author | Sahputra R | Year | 2018 |
Journal | Eur J Immunol | Volume | 48 |
Issue | 12 | Pages | 2068-2071 |
PubMed ID | 30315705 | Mgi Jnum | J:269485 |
Mgi Id | MGI:6259985 | Doi | 10.1002/eji.201847735 |
Citation | Sahputra R, et al. (2018) Evaluating the IgMi mouse as a novel tool to study B-cell biology. Eur J Immunol 48(12):2068-2071 |
abstractText | The IgMi mouse fails to secrete antibodies or class switch its BCR from IgM. Our study reveals that other cellular compartments, including B-cell subsets, DC subsets, GC B cells and TFH cells are perturbed in the IgMi mouse, thus presenting important additional considerations when using the mouse to explore the role of secreted antibody. |