| First Author | Carmody R | Year | 2017 |
| Journal | Cancer Cell | Volume | 31 |
| Issue | 5 | Pages | 612-613 |
| PubMed ID | 28486101 | Mgi Jnum | J:242578 |
| Mgi Id | MGI:5905688 | Doi | 10.1016/j.ccell.2017.04.011 |
| Citation | Carmody R, et al. (2017) The Tribble with APL: A New Road to Therapy. Cancer Cell 31(5):612-613 |
| abstractText | The t(15;17) translocation generates a PML-RARalpha fusion protein causative for acute promyelocytic leukemia (APL). Li et al. now identify the pseudokinase stress protein TRIB3 as an important factor in APL disease progression and therapy resistance. Targeting the interaction of TRIB3 and PML-RARalpha using peptide technology provides a novel therapeutic approach. |
