| Type | MGI:General | Description | at 7 months of age, 5 of 8 males show moderate to severe vacuolization of seminiferous tubules, with >10% vacuolated tubules per cross section severe intracytoplasmic vacuolization begins in the tubular epithelium more centrally within the tubule and progresses to the periphery, sparing the Sertoli cells severely affected males show numerous seminiferous tubules that are completely devoid of germ cells, containing only Sertoli cells less affected tubules show spermatid heads near the basement membrane and meiotic stages interspersed with haploid germ cell stages |
