| Primary Identifier | IPR029651 | Type | Family |
| Short Name | EPG-5 |
| description | Autophagy involves the formation of a double-membrane structure, called the autophagosome, which engulfs portions of the cytosol and delivers them to lysosomes for degradation. It plays critical roles, including ridding the cell of damaged organelles and proteins, generating nutrients forcell survival under starvation, and elimination of pathogens []. This entry consists of C.elegans ectopic P granules protein 5 (EPG-5) from C.elegans and its homologues. It has a role in the degradation of protein aggregates within autophagosomes []. Recessive mutations in EPG5 cause the multisystem disorder with defective autophagy known as Vici syndrome []. |
