Primary Identifier | MGI:4821341 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(Gcg-GH1)#Herr |
Strain of Origin | (C57BL/6J x CBA/J)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The construct consisted of the 2.1 kb rat glucagon promoter, a loxP-STOP-loxP sequence and the human growth hormone gene (GH1; hGH). (C57BL/6J x CBA/J)F2 zygotes were injected and at least three founder lines were generated and a line with stable and complete transgene expression (i.e. in about 100% of targeted cells) was established. Crosses with cre-expressing animals will excise the STOP signal, resulting in GH1 expression as a tag. |