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Protein Coding Gene : Gpr108 G protein-coupled receptor 108

Primary Identifier  MGI:1925558 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  78308
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in negative regulation of toll-like receptor signaling pathway. Located in cis-Golgi network membrane. Orthologous to human GPR108 (G protein-coupled receptor 108).
PHENOTYPE: Mice homozygous for a null allele exhibit increased LPS-induced mortality. [provided by MGI curators]
  • synonyms:
  • 1810015L19Rik,
  • C79132,
  • G protein-coupled receptor 108,
  • MGI:2146772,
  • expressed sequence C79132,
  • MGI:2147129,
  • expressed sequence AA589464,
  • RIKEN cDNA 1810015L19 gene,
  • AA589464,
  • Gpr108

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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