| Primary Identifier | IPR012112 | Type | Family |
| Short Name | REV1 |
| description | Rev1 is a deoxycytidyl transferase involved in translesion DNA synthesis (TLS) pathway to bypass DNA lesions during replication []. During TLS, Y-family DNA polymerase (Poleta, Polkappa, Poliota and Rev1) incorporates a nucleotide opposite the DNA lesion, and then Polzeta (consitst of Rev3 and Rev7) carries out primer extension. Rev1 is a unique member of the Y polymerase family, since its catalytic activity is limited to DNA-dependent, deoxycytidyl transferase activity [, , ]. |
