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Allele : Brca1<tm4Cxd> breast cancer 1, early onset; targeted mutation 4, Chu-Xia Deng

Primary Identifier  MGI:3665173 Allele Type  Targeted
Attribute String  Hypomorph, Inserted expressed sequence, Modified isoform(s) Gene  Brca1
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A gene fragment including part of exon 11 and all of intron 11 and exon 12 was replaced with a cDNA that results in joining of exon 11 to all exons 3' of exon 11. RT-PCR and Northern blot analysis confirmed the absence of transcript of the alternative splicing form of Brca1 that lacks exon 11; however, full length transcript is present.
  • mutations:
  • Insertion
  • synonyms:
  • Brca1<FL>,
  • Brca1<FL>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele