| Primary Identifier | MGI:98363 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 20670 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including positive regulation of G0 to G1 transition; positive regulation of satellite cell activation involved in skeletal muscle regeneration; and trophoblast giant cell differentiation. Acts upstream of or within several processes, including myoblast development; negative regulation of striated muscle tissue development; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; gut; incisor; and integumental system. Orthologous to human SOX15 (SRY-box transcription factor 15). PHENOTYPE: Mice homozygous for disruptions in this gene display abnormalities in muscle fiber differentiation and in muscle regeneration after injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
