| Type | MGI:General | Description | following reperfusion of an ischemic heart ex vivo, rate pressure product is increased (16+/-1.3 compared to 10+/-2.1 beats per minute mm Hg x10-3 in wild-type mice), cardiac work is increased (5.7+/-0.6 compared to 2.3+/-0.8 ml per minute mm Hg x10-2 in wild-type mice), aortic flow is increased (5.5+/-0.9 compared to 1.5+/-0.6 ml per minute in wild-type mice), and cardiac power is increased (61.4+/-6.9 compared to 25.2+/-9.1 mJ per minute in wild-type mice) recovery after cardiac ischemia is improved 2.5-fold compared to in wild-type mice and mice recover almost 80% of their preischemic values |
