| First Author | Iwaoki Y | Year | 1993 |
| Journal | Exp Cell Res | Volume | 206 |
| Issue | 2 | Pages | 212-9 |
| PubMed ID | 7684693 | Mgi Jnum | J:12878 |
| Mgi Id | MGI:61094 | Doi | 10.1006/excr.1993.1140 |
| Citation | Iwaoki Y, et al. (1993) Differential expression of the proto-oncogenes c-abl and c-mos in developing mouse germ cells. Exp Cell Res 206(2):212-9 |
| abstractText | C-abl and c-mos, two proto-oncogenes with unique patterns of expression in gonadal tissues, were examined by in situ hybridization with respect to their expression in the germ line. C-abl transcripts were observed to be most abundant in late round spermatids and elongating spermatids. C-mos transcripts were also expressed in round spermatids, but at much reduced levels compared to the levels of c-abl. C-abl mRNAs were also detected in mouse oocytes which have entered the growth phase. This temporal specificity of accumulation of c-abl transcripts was similar to that observed for c-mos, which also accumulates in growing and fully grown oocytes (follicle stages 4-6). Quantitative evaluation suggested that c-abl mRNA levels in oocytes are at least an order of magnitude lower than those of c-mos transcripts. |
