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Protein Coding Gene : Ttc21a tetratricopeptide repeat domain 21A
Primary Identifier  MGI:1921302 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  74052
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in flagellated sperm motility and spermatid development. Predicted to be part of intraciliary transport particle A. Is expressed in 4th ventricle; choroid plexus; lateral ventricle choroid plexus; and olfactory epithelium. Human ortholog(s) of this gene implicated in spermatogenic failure 37. Orthologous to human TTC21A (tetratricopeptide repeat domain 21A).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit male infertility and asthenoteratospermia characterized by reduced sperm motility and multiple sperm malformations affecting the flagella and the connecting piece. [provided by MGI curators]
  • synonyms:
  • MGI:3035025,
  • Thm2,
  • 4921538N17Rik,
  • RIKEN cDNA 4921538N17 gene,
  • expressed sequence AA387572,
  • AA387572,
  • Ttc21a,
  • tetratricopeptide repeat domain 21A
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Trail: ProteinCodingGene




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