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Protein Coding Gene : Ppp2cb protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform

Primary Identifier  MGI:1321161 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  19053
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable protein serine/threonine phosphatase activity and transmembrane transporter binding activity. Acts upstream of or within several processes, including apoptotic mitochondrial changes; proteasome-mediated ubiquitin-dependent protein catabolic process; and response to hydrogen peroxide. Located in cytoplasm. Part of protein phosphatase type 2A complex. Is expressed in several structures, including cardiovascular system; central nervous system; eye; genitourinary system; and gut. Orthologous to human PPP2CB (protein phosphatase 2 catalytic subunit beta).
PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile. [provided by MGI curators]
  • synonyms:
  • PP2Ac,
  • MGI:2142462,
  • expressed sequence AI115466,
  • AI115466,
  • DNA segment, Chr 8, ERATO Doi 766, expressed,
  • MGI:1289237,
  • Ppp2cb,
  • protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform,
  • D8Ertd766e

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

101 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For