Primary Identifier | MGI:1914659 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 383348 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0) Predicted to enable G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential and G protein-coupled neurotransmitter receptor activity involved in regulation of presynaptic membrane potential. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Located in postsynaptic membrane and presynaptic membrane. Part of receptor complex. Is expressed in autopod; central nervous system; dorsal root ganglion; sensory organ; and trachea. Orthologous to human KCTD16 (potassium channel tetramerization domain containing 16). PHENOTYPE: Homozygous knockout leads to reduced extinction or increase of fear memory in cued or contextual conditioning behavior tests, respectively. [provided by MGI curators] |