| Type | MGI:General | Description | mutants exhibit impaired T cell-mediated immune reaction in a model of contact hypersensitivity, characterized by abrogated ear swelling and thickening of the epidermis, reduced influx of inflammatory cells, low proliferation of keratinocytes, and reduced number of activated CD8+ T cells in draining lymph nodes after cutaneous sensitization and challenge by FITC painting on the ear |
