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Comment :

Type  MGI:General Description  after intranasal administration of house dust mites (HDMs) to induce allergic airway inflammation, mice exhibit a lower infiltration of eosinophils in their lungs relative to heterozygous controls, as determined by eosinophil cell % of lung CD45+ immune cells immunostaining of Siglec-F (which labels the populations of eosinophils and alveolar macrophages), confirmed reduced eosinophil abundance in the lung tissues after HDM treatment