Primary Identifier | MGI:2656627 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Amot |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by replacement of the splice acceptor site of the second exon with a PGK-neo cassette via homologous recombination. RT-PCR sequence analysis showed the mutant allele contains a frameshift and premature stop codon, therefore no functional protein product should be translated. |