Primary Identifier | MGI:5828622 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Fgfr1 |
Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 10 was replaced with one in which nucleotide substitutions result in a silent mutation and the amino acid substitution of phenylalanine for tyrosine at position 463 (Y463F). Exon 18 was replaced with one in which nucleotide substitutions result in the amino acid substitution of phenylalanine for tyrosine at positions 766 and 776 (Y766F, Y776F). Cre-mediated recombination removed the floxed neomycin resistance cassette inserted in intron 9. |