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Allele : Fgfr1<tm8.1Sor> fibroblast growth factor receptor 1; targeted mutation 8.1, Philippe Soriano

Primary Identifier  MGI:5828622 Allele Type  Targeted
Attribute String  Not Specified Gene  Fgfr1
Transmission  Germline Strain of Origin  129S4/SvJaeSor
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 10 was replaced with one in which nucleotide substitutions result in a silent mutation and the amino acid substitution of phenylalanine for tyrosine at position 463 (Y463F). Exon 18 was replaced with one in which nucleotide substitutions result in the amino acid substitution of phenylalanine for tyrosine at positions 766 and 776 (Y766F, Y776F). Cre-mediated recombination removed the floxed neomycin resistance cassette inserted in intron 9.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Fgfr1CPG,
  • Fgfr1<CPG>,
  • Fgfr1CPG,
  • Fgfr1<CPG>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele