Primary Identifier | MGI:3604808 | Allele Type | Targeted |
Attribute String | Hypomorph | Gene | Npm1 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An Frt-flanked neomycin resistance cassette was inserted into intron 6. Mutant mice expressed protein at levels reduced to about 10-30% of wild-type levels. LoxP sites were inserted to flank exons 1 to 6, encompassing the inserted neo. |