| Primary Identifier | MGI:107714 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 13417 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and minus-end-directed microtubule motor activity. Predicted to be involved in cilium movement involved in cell motility and outer dynein arm assembly. Predicted to be located in axoneme. Predicted to be part of outer dynein arm. Predicted to be active in sperm flagellum. Is expressed in brain and thymus primordium. Used to study spermatogenic failure 46. Human ortholog(s) of this gene implicated in spermatogenic failure 46. Orthologous to human DNAH8 (dynein axonemal heavy chain 8). PHENOTYPE: Mice homozygous for a null allele exhibit male infertility due to sperm immobility and malformed and/or absent flagella. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
