Primary Identifier | MGI:1274787 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 13434 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables tRNA (cytidine-5-)-methyltransferase activity. Involved in tRNA methylation and tRNA stabilization. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; olfactory epithelium; and thyroid gland. Orthologous to human TRDMT1 (tRNA aspartic acid methyltransferase 1). PHENOTYPE: Mice homozygous for disruptions in this gene have a decreased proportion of natural killer cells in the peripheral blood. [provided by MGI curators] |