Primary Identifier | MGI:1888978 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 57764 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables laminin-1 binding activity. Acts upstream of or within neuron remodeling and regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling. Located in basement membrane. Is expressed in several structures, including alimentary system; cardiovascular system; connective tissue; genitourinary system; and nervous system. Orthologous to human NTN4 (netrin 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased cell proliferation in the cornea without an increase in corneal thickness and increased microvessel branching in the middle levels of the retina. [provided by MGI curators] |