| Type | MGI:General | Description | homozygotes are viable, healthy and show no obvious neurological abnormalities, such as ataxia, up to 18 months of age however, chow-fed homozygotes exhibit a >90% reduction of alpha-tocopherol levels in plasma and most tissues notably, in liver, adipose tissue, adrenal gland, and aorta, alpha-tocopherol levels are only 15-35% of wild-type levels |
