Primary Identifier | MGI:3764670 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence | Gene | Tg(Myh6/tetO-BNIP3)1Gwd |
Induced With | doxycycline/tetracycline | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A tetracycline-responsive Myh6 promoter was fused to a cDNA encoding human BNIP3. Immunoreactivity following activation of this transgene is increased 50-fold without changing the relative abundance of major cardiac anti-apoptotic Bcl2 family proteins. |