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Allele : Gfi1<em1Hlg> growth factor independent 1 transcription repressor; endonuclease-mediated mutation 1, H Leighton Grimes

Primary Identifier  MGI:6512040 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Gfi1
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  The zinc finger nuclease induced mutation creates an R412X mutation in exon 6 resulting in a premature stop codon. The mutation is identified in patients with severe congenital neutropenia (SCN).
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • GFI<R412X>,
  • GFI<R412X>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele