Primary Identifier | MGI:6512040 | Allele Type | Endonuclease-mediated |
Attribute String | Humanized sequence | Gene | Gfi1 |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The zinc finger nuclease induced mutation creates an R412X mutation in exon 6 resulting in a premature stop codon. The mutation is identified in patients with severe congenital neutropenia (SCN). |