| Experiment Id | GSE234068 | Name | Meiotic completion of the spermatocytes requires the kinase WNK1 |
| Experiment Type | RNA-Seq | Study Type | WT vs. Mutant |
| Source | GEO | Curation Date | 2024-10-18 |
| description | The kinase protein WNK1 is highly expressed and phosphorylated in the testis, suggesting possible functions in regulating male fertility. Indeed, conditional pachytene-spermatocyte Wnk1 knock-out mice generated using the novel Wnt7a-Cre failed to produce functional sperm which resulted from the primary spermatogenic arrest during mid-pachynema. Global transcriptomic approaches identified 'translation' as one of the impacted events in Wnk1-depleted spermatocytes. scRNA-seq profiling of Wnk1-depleted and control spermatocytes |
