| First Author | Shirai K | Year | 2004 |
| Journal | Ophthalmic Res | Volume | 36 |
| Issue | 4 | Pages | 226-30 |
| PubMed ID | 15292661 | Mgi Jnum | J:93107 |
| Mgi Id | MGI:3055827 | Doi | 10.1159/000078782 |
| Citation | Shirai K, et al. (2004) Expression of c-Fos and c-Jun in developing mouse lens. Ophthalmic Res 36(4):226-30 |
| abstractText | We carried out immunohistochemistry in embryonic eye-specific antibodies in the mouse to determine the spatial/temporal expression pattern of c-Fos and c-Jun proteins--the main components of the AP-1 transcription factor, in lens epithelial cells during mouse lens morphogenesis. c-Fos protein expression was detected in the equatorial epithelium at E14.5-P25, with a peak at P1-P8. c-Jun protein expression was detected in equatorial lens epithelial cells at E18.5-P8, with a peak at P1. During these intervals, the anterior epithelium lacked expression of c-Fos and c-Jun. They were not detected in an adult mouse lens. The expression pattern of the AP-1 transcription factor in equatorial epithelium may suggest its role in fiber differentiation. |
