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Allele : Plcg2<tm1Ichi> phospholipase C, gamma 2; targeted mutation 1, Hirotake Ichise
Primary Identifier  MGI:3833397 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Plcg2
Transmission  Germline Strain of Origin  129S/SvEv and C57BL/6J
Is Recombinase  false Is Wild Type  false
description  The ES cell line used to generate this allele was established from Plcg2+/Plcg2al blastocysts. All correctly targeted clones possessed the Plcg2+/Plcg2tm1Ichi genotype.
molecularNote  Part of the coding region of exon 2 was replaced with EGFP cDNA followed by a murine PGK polyadenylation signal sequence and an FRT-flanked PGK-gb2-neo cassette. Newborn heart tissue lysates from homozygous mutant animals did not contain protein product as determined by Western blot.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Plcg2<EGFP>,
  • PLCgamma2-null,
  • Plcg2<EGFP>,
  • PLCgamma2-null
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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