Primary Identifier | MGI:2661203 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph, Reporter | Gene | Rtn4 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The amino and carboxy terminals were targeted in cis to generate an allele from which no protein is produced. The amino terminal was disrupted by the insertion of IRES-GFPLacZ-loxP and an frt-flanked hprt cassette. A floxed neo cassette disrupted the carboxy terminal exon encoding the first transmembrane domain, common to all isoforms. |