First Author | Weiss EH | Year | 1984 |
Journal | Nature | Volume | 310 |
Issue | 5979 | Pages | 650-5 |
PubMed ID | 6088985 | Mgi Jnum | J:7562 |
Mgi Id | MGI:56032 | Doi | 10.1038/310650a0 |
Citation | Weiss EH, et al. (1984) Organization and evolution of the class I gene family in the major histocompatibility complex of the C57BL/10 mouse. Nature 310(5979):650-5 |
abstractText | The major histocompatibility complex (MHC) encodes several classes of protein vital to the regulation of the immune response. We have isolated 26 class I genes that map to this region in the C57BL/10 mouse and linked these into three gene clusters. The number of genes differs from the number found in the BALB/c strain and comparison of the organization of the class I genes in these two strains shows conserved regions and polymorphic regions which probably result from deletions, insertions and translocations within the MHC. |