Primary Identifier | MGI:1918320 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 217588 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Involved in regulation of cell cycle; regulation of cell division; and regulation of embryonic development. Located in nucleus. Part of ATAC complex. Is expressed in lung and telencephalon. Orthologous to human MBIP (MAP3K12 binding inhibitory protein 1). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality by E7.5. In vitro outgrowth assays show that blastocysts hatch from the zona pellucida but form irregular outgrowths. [provided by MGI curators] |